Note: *, co-first authors;  **, co-correspondence authors.

[2019] [2018] [2017] [2016] [2015] [2014] [2013] [2012] [2011] [2010] [2008] [2002] [2001] [2000]

2019

  • Wang, L. W., Wang, Z., Ersing, I., Nobre, L., Guo, R., Jiang, S., Trudeau, S., Zhao, B., Weekes, M. P. & Gewurz, B. E. Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival. PLOS Pathogens 15, 1-35 (2019).
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  • Wang, L. W., Shen, H., Nobre, L., Ersing, I., Paulo, J. A., Trudeau, S., Wang, Z., Smith, N. A., Ma, Y., Reinstadler, B., Nomburg, J., Sommermann, T., Cahir-McFarland, E., Gygi, S. P., Mootha, V. K., Weekes, M. P. & Gewurz, B. E. Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation. Cell Metabolism (2019). doi:10.1016/j.cmet.2019.06.003
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  • Jiang, C., Trudeau, S. J., Cheong, T. -C., Guo, R., Teng, M., Wang, L. W., Wang, Z., Pighi, C., Gautier-Courteille, C., Ma, Y., Jiang, S., Wang, C., Zhao, B., Paillard, L., Doench, J. G., Chiarle, R. & Gewurz, B. E. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Reports 28, 1307--1322.e8 (2019).
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2018

  • Wang, L. W., Trudeau, S. J., Wang, C., Gerdt, C., Jiang, S., Zhao, B. & Gewurz, B. E. Modulating Gene Expression in Epstein-Barr Virus (EBV)-Positive B Cell Lines with CRISPRa and CRISPRi. Current Protocols in Molecular Biology 121, 1-31 (2018).
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  • Jiang, S., Wang, L. W., Walsh, M. J., Trudeau, S. J., Gerdt, C., Zhao, B. & Gewurz, B. E. CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell Lines. Current Protocols in Molecular Biology 121, (2018).
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  • Gebre, M., Nomburg, J. L. & Gewurz, B. E. CRISPR–Cas9 Genetic Analysis of Virus–Host Interactions. Viruses 10, (2018).
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  • Zhang, H., Li, Y., Wang, H. -B., Zhang, A., Chen, M. -L., Fang, Z. -X., Dong, X. -D., Li, S. -B., Du, Y., Xiong, D., He, J. -Y., Li, M. -Z., Liu, Y. -M., Zhou, A. -J., Zhong, Q., Zeng, Y. -X., Kieff, E., Zhang, Z., Gewurz, B. E., Zhao, B. & Zeng, M. -S. Ephrin receptor A2 is an epithelial cell receptor for Epstein–Barr virus entry. Nature Microbiology 3, 164--171 (2018).
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2017

  • Wang, L. W., Jiang, S. & Gewurz, B. E. Epstein-Barr Virus LMP1-Mediated Oncogenicity. Journal of Virology 91, (2017).
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  • Jiang, S., Zhou, H., Liang, J., Gerdt, C., Wang, C., Ke, L., Schmidt, S. C. S., Narita, Y., Ma, Y., Wang, S., Colson, T., Gewurz, B., Li, G., Kieff, E. & Zhao, B. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. Cell Host & Microbe 22, 561 - 573.e4 (2017).
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  • Ersing, I. *, Nobre, L. *, Wang, L. W., Soday, L., Ma, Y., Paulo, J. A., Narita, Y., Ashbaugh, C. W., Jiang, C., Grayson, N. E., Kieff, E., Gygi, S. P., Weekes, M. P. ** & Gewurz, B. E. **. A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells. Cell Reports 19, 1479--1493 (2017).
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  • Ma, Y. *, Walsh, M. J. *, Bernhardt, K., Ashbaugh, C. W., Trudeau, S. J., Ashbaugh, I. Y., Jiang, S., Jiang, C., Zhao, B., Root, D. E., Doench, J. G. & Gewurz, B. E. CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host & Microbe 21, 580--591.e7 (2017).
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  • Minamitani, T. *, Ma, Y. *, Zhou, H., Kida, H., Tsai, C. -Y., Obana, M., Okuzaki, D., Fujio, Y., Kumanogoh, A., Zhao, B., Kikutani, H., Kieff, E. **, Gewurz, B. E. ** & Yasui, T. **. Mouse model of Epstein–Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease. Proceedings of the National Academy of Sciences 114, 4751-4756 (2017).
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2016

  • Hunter, J. E., Butterworth, J. A., Zhao, B., Sellier, H., Campbell, K. J., Thomas, H. D., Bacon, C. M., Cockell, S. J., Gewurz, B. E. & Perkins, N. D. The NF-kappaB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene 35, 3476-3484 (2016).
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  • Blondel, C.  J., Park, J.  S., Hubbard, T.  P., Pacheco, A.  R., Kuehl, C.  J., Walsh, M.  J., Davis, B.  M., Gewurz, B.  E., Doench, J.  G. & Waldor, M.  K. CRISPR/Cas9 Screens Reveal Requirements for Host Cell Sulfation and Fucosylation in Bacterial Type \III\ Secretion System-Mediated Cytotoxicity. Cell Host & Microbe 20, 226 - 237 (2016).
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2015

  • Minamitani, T., Yasui, T., Ma, Y., Zhou, H., Okuzaki, D., Tsai, C. -Y., Sakakibara, S., Gewurz, B. E., Kieff, E. & Kikutani, H. Evasion of affinity-based selection in germinal centers by Epstein–Barr virus LMP2A. Proceedings of the National Academy of Sciences 112, 11612-11617 (2015).
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  • Zhou, H., Schmidt, S.  C. S., Jiang, S., Willox, B., Bernhardt, K., Liang, J., Johannsen, E.  C., Kharchenko, P., Gewurz, B.  E., Kieff, E. & Zhao, B. Epstein-Barr Virus Oncoprotein Super-enhancers Control B Cell Growth. Cell Host & Microbe 17, 205 - 216 (2015).
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  • Greenfeld, H., Takasaki, K., Walsh, M. J., Ersing, I., Bernhardt, K., Ma, Y., Fu, B., Ashbaugh, C. W., Cabo, J., Mollo, S. B., Zhou, H., Li, S. & Gewurz, B. E. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLOS Pathogens 11, 1-35 (2015).
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2014

  • Zhao, B., Barrera, L.  A., Ersing, I., Willox, B., Schmidt, S.  C. S., Greenfeld, H., Zhou, H., Mollo, S.  B., Shi, T.  T., Takasaki, K., Jiang, S., Cahir-McFarland, E., Kellis, M., Bulyk, M.  L., Kieff, E. & Gewurz, B.  E. The NF-κB Genomic Landscape in Lymphoblastoid B Cells. Cell Reports 8, 1595 - 1606 (2014).
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  • Zhou, X., Massol, R. H., Nakamura, F., Chen, X., Gewurz, B. E., Davis, B. M., Lencer, W. I. & Waldor, M. K. Remodeling of the Intestinal Brush Border Underlies Adhesion and Virulence of an Enteric Pathogen. mBio 5, (2014).
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  • Iannetti, A., Ledoux, A. C., Tudhope, S. J., Sellier, H., Zhao, B., Mowla, S., Moore, A., Hummerich, H., Gewurz, B. E., Cockell, S. J., Jat, P. S., Willmore, E. & Perkins, N. D. Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence. PLOS Genetics 10, 1-20 (2014).
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2013

  • Ersing, I., Bernhardt, K. & Gewurz, B. E. NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1. Viruses 5, 1587 (2013).
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  • Zhou*, X., Gewurz*, B.  E., Ritchie, J.  M., Takasaki, K., Greenfeld, H., Kieff, E., Davis, B.  M. & Waldor, M.  K. A Vibrio parahaemolyticus \T3SS\ Effector Mediates Pathogenesis by Independently Enabling Intestinal Colonization and Inhibiting \TAK1\ Activation. Cell Reports 3, 1690 - 1702 (2013).
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2012

  • Gewurz, B. E., Towfic, F., Mar, J. C., Shinners, N. P., Takasaki, K., Zhao, B., Cahir-McFarland, E. D., Quackenbush, J., Xavier, R. J. & Kieff, E. Genome-wide siRNA screen for mediators of NF-κB activation. Proceedings of the National Academy of Sciences 109, 2467-2472 (2012).
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2011

  • Zhao, B., Mar, J. C., Maruo, S., Lee, S., Gewurz, B. E., Johannsen, E., Holton, K., Rubio, R., Takada, K., Quackenbush, J. & Kieff, E. Epstein–Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines. Proceedings of the National Academy of Sciences 108, 337-342 (2011).
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  • Gewurz, B. E., Mar, J. C., Padi, M., Zhao, B., Shinners, N. P., Takasaki, K., Bedoya, E., Zou, J. Y., Cahir-Mcfarland, E., Quackenbush, J. & Kieff, E. Canonical NF-κB Activation Is Essential for Epstein-Barr Virus Latent Membrane Protein 1 TES2/CTAR2 Gene Regulation. Journal of Virology 85, 6764-6773 (2011).
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2010

  • Boehm, D., Gewurz, B. E., Kieff, E. & Cahir-McFarland, E. Epstein-Barr latent membrane protein 1 transformation site 2 activates NF-κB in the absence of NF-κB essential modifier residues 133–224 or 373–419. Proceedings of the National Academy of Sciences 107, 18103-18108 (2010).
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2008

  • Song, Y. -J., Izumi, K. M., Shinners, N. P., Gewurz, B. E. & Kieff, E. IRF7 activation by Epstein–Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3. Proceedings of the National Academy of Sciences 105, 18448--18453 (2008).
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2002

  • Gewurz, B. E., Ploegh, H. L. & Tortorella, D. US2, a Human Cytomegalovirus-encoded Type I Membrane Protein, Contains a Non-cleavable Amino-terminal Signal Peptide. Journal of Biological Chemistry 277, 11306-11313 (2002).
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2001

  • Gewurz, B. E., Wang, E. W., Tortorella, D., Schust, D. J. & Ploegh, H. L. Human Cytomegalovirus US2 Endoplasmic Reticulum-Lumenal Domain Dictates Association with Major Histocompatibility Complex Class I in a Locus-Specific Manner. Journal of Virology 75, 5197-5204 (2001).
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  • Gewurz, B. E., Gaudet, R., Tortorella, D., Wang, E. W. & Ploegh, H. L. Virus subversion of immunity: a structural perspective. Current Opinion in Immunology 13, 442 - 450 (2001).
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  • Gewurz, B. E., Gaudet, R., Tortorella, D., Wang, E. W., Ploegh, H. L. & Wiley, D. C. Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proceedings of the National Academy of Sciences 98, 6794-6799 (2001).
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2000

  • Tortorella, D., Gewurz, B. E., Furman, M. H., Schust, D. J. & Ploegh, H. L. Viral Subversion of the Immune System. Annual Review of Immunology 18, 861-926 (2000).
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