Laura joins us following her PhD studies at Princeton, where she studied human cytomegalovirus in the lab of Ileana Cristea. Laura used whole cell proteomic profiling to characterize roles of protein acetylation in host defense and HCMV replication and characterized roles of lamin B1 acetylation. She also studied the temporal dynamics of complex formation during HCMV infection.
Yifei joins us after completing PhD studies with Sanjay Reddy and Blanca Lupiani at Texas A&M. Yifei’s doctoral studies focused on the alpha-herpesvirus Marek’s Disease Virus, an important avian tumor virus. Yifei studied roles of the US3 kinase, the MEQ oncoprotein and miRNAs.
Jewel is a summer research intern visiting from University of Rhode Island. Jewel is a member of the Harvard SHURP program and working with Eric and Eshaani to study the the ferroptosis pathway in EBV-transformed cells .
Eshaani did her doctoral studies in virology with Dr. Haitao Guo at University of Indiana and subsequently at University of Pittsburgh studying Hepatitis B virus (HBV) host/pathogen interactions. Eshaani found that HBV precore protein p22 inhibits alpha interferon signaling by blocking stat nuclear translocation.
Prior to matriculating in the Harvard Graduate Program in Virology, Stephanie did research in Alan Chiang’s laboratory on EBV lytic reactivation in nasopharyngeal carcinoma. Stephanie is pursuing proteomic analyses of EBV host-pathogen interactions and studying a novel innate immune pathway subverted by EBV in newly infected B-cells and cells undergoing lytic replication.
Yuchen is purusing her graduate studies, with a focus on how host histone chaperones regulate EBV latency in EBV-transformed B-cells. Check out her preprint on BioRxiv!
Jin Hua is pursuing graduate research in the Gewurz lab. Jin Hua’s research focuses on the regulation of nucleotide metabolism and NF-kB in EBV-transformed B-cells.
Merrin Leong did his doctoral research at Hong Kong University in the laboratory of Maria Lung, where he studied Epstein-Barr virus infection roles in regulation of host histone modifications. Merring identified that EBV infections induces histone bivalent switches in squameous epithelial cells, and found roles for these epigenetic modifiations in suppression of DNA damage repair genes in a methylation-independent manner.
Eric Burton received his PhD from Stonybrook University. Eric’s doctoral research with Sumita Bhaduri-McIntosh focused on host pathogen interactions that regulate the EBV lytic cycle. Eric identified that EBV exploits several inflammasome sensors to activate the lytic cycle, in particular the NLRP3 inflammasome. He also identified host repressors important for the maintenance of EBV latency.
Rui Guo received his PhD from Kansas State, where his thesis research with Ying Fan focused on procine reproductive and respiratory virus syndrome host/pathogen interactions. He discovered that PRSSV uses nanotubes for intracellular spread, that nanotubes also transfer mitochondria between nearby and infected cells, and that PRSSV RNA persists in germinal centers during persistent infection.